I have gone over all documentation multiple times and I've been using CC3 faithfully for the last couple of years. Since the last couple of CC3 updates, retargeting any Epic skeleton animation to an imported CC3 skeleton is off on the hands/arms area. This has also been tested against other 3rd party character software and there's no issues with retargetting. After speaking with multiple CC3 users i have found this to be a common issue amongst all of them. This is a very serious issue and i can't seem to find a workaround. I've made sure all import/export options are properly checks, and i've tried different CC3 characters of all shapes and sizes.
I made the tests with embedded Katherine, Slacker (apply Pistol Idle motion from UE free Animation Starter Pack via UE retargeting)
Please see the attached images: they hold the gun in both hands and not as serious as your image, could you provide your workflow?
or you can refer this retargeting tutorial video first:
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